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Invitrogen
TFAP2E Polyclonal Antibody
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产品信息
PA5-41689
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human TFAP2E (aa 393-442).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Peptide sequence: FGGPAICAAL TAFQNYLLES LKGLDKMFLS SVGSGHGETK ASEKDAKHRK
Sequence homology: Cow: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100%
靶标信息
TFAP2E is the sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 epsilon may play a role in the development of the CNS and in cartilage differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activating enhancer-binding protein 2-epsilon; adaptor-related protein complex 2, epsilon subunit; AP2-epsilon; MGC49007; TFAP2E; transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon); Transcription factor AP-2-epsilon
基因别名: AP2E; TFAP2E
UniProt ID: (Human) Q6VUC0
Entrez Gene ID: (Human) 339488
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein homodimerization activity
protein heterodimerization activity
general transcription factor
