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TFF1 Antibody (PA5-42776) in WB
Western blot was performed using Anti-TFF1 Polyclonal Antibody (Product # PA5-42776) and a 9kDa band corresponding to Trefoil factor 1 was observed across was observed in MCF7 cell line and showed upregulation upon treatment with beta-estradiol as opposed to MDA-MB-231 or MCF 10A. Whole-cell extracts (30 µg lysate) of MCF7 (Lane 1), MCF7 treated with beta-estradiol (10 nanomolar for 24h) ( (Lane 2), MCF7 (Lane 3), MCF7 treated with PTI (1X for 4h) (Lane 4), MDA-MB-231 (Lane 5), MDA-MB-231 treated with PTI (1X for 4h) (Lane 6), MCF 10A (Lan... View More
Product Details
PA5-42776
产品规格
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human TFF1
Conjugate
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2609755
Product Specific Information
Peptide sequence: PRERQNCGFP GVTPSQCANK GCCFDDTVRG VPWCFYPNTI DVPPEEECEF
Sequence homology: Human: 100%
Target Information
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: Breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence; gastrointestinal trefoil protein pS2; hP1.A; PNR-2; Polypeptide P1.A; Protein pS2; Trefoil factor 1
Gene Aliases: BCEI; D21S21; HP1.A; HPS2; pNR-2; PS2; TFF1
UniProt ID: (Human) P04155
Entrez Gene ID: (Human) 7031
Molecular Function:
intercellular signal molecule
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