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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
流式细胞分析 (Flow) |
1:200-1:400 | - |
酶联免疫吸附实验 (ELISA) |
1:10,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
4G7C3 |
抗原 |
Purified recombinant fragment of human TFF2 (AA: 20-125) expressed in E. coli. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Protein G |
保存液 |
PBS |
内含物 |
0.05% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2787553 |
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of the gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. A downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SP; Spasmolysin; Spasmolytic polypeptide; spasmolytic protein 1; Trefoil factor 2
基因别名: SML1; SP; TFF2
UniProt ID: (Human) Q03403
Entrez Gene ID: (Human) 7032
分子生物学功能:
intercellular signal molecule
