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Invitrogen
TGFBR2 Polyclonal Antibody
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产品信息
PA5-88247
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 237-549 of human TGF beta Receptor II (TGFBR2) (NP_0032334)
偶联物
形式
Liquid
浓度
0.53 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: HNTELLPIEL DTLVGKGRFA EVYKAKLKQN TSEQFETVAV KIFPYEEYAS WKTEKDIFSD INLKHENILQ FLTAEERKTE LGKQYWLITA FHAKGNLQEY LTRHVISWED LRKLGSSLAR GIAHLHSDHT PCGRPKMPIV HRDLKSSNIL VKNDLTCCLC DFGLSLRLDP TLSVDDLANS GQVGTARYMA PEVLESRMNL ENVESFKQTD VYSMALVLWE MTSRCNAVGE VKDYEPPFGS KVREHPCVES MKDNVLRDRG RPEIPSFWLN HQGIQMVCET LTECWDHDPE ARLTAQCVAE RFSELEHLDR LSG
Positive Samples: HT-29, A-549, Mouse lung; Cellular Location: Cell membrane, Single-pass type I membrane protein
靶标信息
Transforming Growth Factor, beta receptor 2 (AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor Serine/Threonine kinases. It is involved in the regulation of cell proliferation. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). TGFBR2 encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. TGFBR2 also has a pseudogene on chromosome 14.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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