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Invitrogen
TGFBRAP1 Polyclonal Antibody
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产品信息
PA5-58374
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RQQLFHTLLA IYLHAGPTAH ELAVAAVDLL NRHATEFDAA QVLQMLPDTW SVQLLCPFLM GAMRDSIHAR RTMQVALGLA RSENLIYTYD KMKLKG
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 85%.
靶标信息
Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: TGF-beta receptor-associated protein 1; Transforming growth factor-beta receptor-associated protein 1; VPS3 CORVET complex subunit
基因别名: TGFBRAP1; TRAP-1; TRAP1; VPS3
UniProt ID: (Human) Q8WUH2
Entrez Gene ID: (Human) 9392
