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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LGDQRYTAPW RAAAQRCLQG LWGRASRD
Highest antigen sequence indentity to the following orthologs: Rat - 75%, Mouse - 82%.
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BG37; G-protein coupled bile acid receptor 1; G-protein coupled receptor GPCR19; GPCR HBG37; hBG37; hGPCR19; M-BAR; Membrane-type receptor for bile acids
基因别名: GPBAR1; TGR5
Entrez Gene ID: (Human) 151306