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PA1-21135 detects Thyroid Hormone Rec., alpha1/alpha2 in Human, Mouse, Rat and Porcine samples.
PA1-21135 has been successfully used in Immunohistochemistry (Paraffin) procedures.
PA1-21135 immunogen corresponds to Synthetic peptide of a.a. 13 to 32 [DPEENSARSPDGKRKRKNGQ] of human TR alpha1 protein..
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。