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FIGURE: 1 / 4
Immunogen sequence: EGHVVKCYWG KESPDMTKNF QQVDYSQWGQ WSQVYGNPQQ YGQYMANGWQ VPPYGVYGQP WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ; Positive Samples: A-549, HeLa, K-562; Cellular Location: Cytoplasm, Cytoplasmic granule, Nucleus
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
Protein Aliases: aging-associated gene 7 protein; Nucleolysin TIAR; RNA binding protein TIAR (TIA-1 related); T-cluster binding protein; TIA-1-related nucleolysin; TIA-1-related protein; Tial 1 cytotoxic granule-associated RNA- binding protein-like 1; Tial1 cytotoxic granule-associated RNA binding protein-like 1; Tial1 cytotoxic granule-associated RNA-binding protein-like 1
Gene Aliases: 5330433G13Rik; AL033329; mTIAR; TCBP; TIAL1; TIAR
UniProt ID: (Human) Q01085, (Mouse) P70318
Entrez Gene ID: (Human) 7073, (Rat) 361655, (Mouse) 21843
Molecular Function:
translation initiation factor
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