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TIAL1 Antibody (PA5-96501) in WB
Western blot analysis of TIAL1 in extracts of various cell lines. Samples were incubated with TIAL1 Polyclonal antibody (Product # PA5-96501) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-96501
Applications
Tested Dilution
Publications
产品规格
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 266-375 of human TIAL1.
Conjugate
Unconjugated
形式
Liquid
浓度
0.73 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2808303
Product Specific Information
Immunogen sequence: EGHVVKCYWG KESPDMTKNF QQVDYSQWGQ WSQVYGNPQQ YGQYMANGWQ VPPYGVYGQP WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ; Positive Samples: A-549, HeLa, K-562; Cellular Location: Cytoplasm, Cytoplasmic granule, Nucleus
Target Information
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: aging-associated gene 7 protein; Nucleolysin TIAR; RNA binding protein TIAR (TIA-1 related); T-cluster binding protein; TIA-1-related nucleolysin; TIA-1-related protein; Tial 1 cytotoxic granule-associated RNA- binding protein-like 1; Tial1 cytotoxic granule-associated RNA binding protein-like 1; Tial1 cytotoxic granule-associated RNA-binding protein-like 1
Gene Aliases: 5330433G13Rik; AL033329; mTIAR; TCBP; TIAL1; TIAR
UniProt ID: (Human) Q01085, (Mouse) P70318
Entrez Gene ID: (Human) 7073, (Rat) 361655, (Mouse) 21843
Molecular Function:
translation initiation factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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