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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:100-1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fusion protein containing a sequence corresponding to amino acids 266-375 of human TIAL1. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
3.02 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808303 |
Immunogen sequence: EGHVVKCYWG KESPDMTKNF QQVDYSQWGQ WSQVYGNPQQ YGQYMANGWQ VPPYGVYGQP WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ; Positive Samples: A-549, HeLa, K-562; Cellular Location: Cytoplasm, Cytoplasmic granule, Nucleus
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: aging-associated gene 7 protein; Nucleolysin TIAR; RNA binding protein TIAR (TIA-1 related); T-cluster binding protein; TIA-1-related nucleolysin; TIA-1-related protein; Tial 1 cytotoxic granule-associated RNA- binding protein-like 1; Tial1 cytotoxic granule-associated RNA binding protein-like 1; Tial1 cytotoxic granule-associated RNA-binding protein-like 1
基因别名: 5330433G13Rik; AL033329; mTIAR; TCBP; TIAL1; TIAR
UniProt ID: (Human) Q01085, (Mouse) P70318
Entrez Gene ID: (Human) 7073, (Rat) 361655, (Mouse) 21843
分子生物学功能:
translation initiation factor
