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Invitrogen
TIM-6 Polyclonal Antibody
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产品信息
PA5-148623
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse TIM-6, Glu24-Ala140
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
TIM-6, or T-cell immunoglobulin and mucin-domain containing-6, is a member of the TIM gene family, which plays a significant role in the regulation of immune responses. The TIM family proteins are type I membrane glycoproteins primarily expressed on the surface of various immune cells, including T cells, B cells, and dendritic cells. Although TIM-6 is less well-characterized compared to other members of the TIM family, such as TIM-1, TIM-3, and TIM-4, it is believed to be involved in modulating immune cell interactions and signaling pathways. TIM proteins are known to participate in processes such as T cell activation, tolerance, and the clearance of apoptotic cells. Dysregulation of TIM family proteins has been associated with autoimmune diseases, allergic responses, and cancer, suggesting that TIM-6 may also play a role in these conditions. Understanding the specific functions and mechanisms of TIM-6 within the immune system is crucial for developing potential therapeutic strategies aimed at modulating immune responses in various diseases. Research into TIM-6 can provide valuable insights into the broader roles of the TIM family in immune regulation and their potential as targets for immunotherapy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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