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Invitrogen
TIMP3 Polyclonal Antibody
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产品信息
PA1-21146
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptidecorresponding to the C-terminal portion of human TIMP-3.
偶联物
形式
Liquid
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
PA1-21146 detects TIMP-3 in rabbit, human and baboon samples. This antibody will not detect rat, bovine, avian, or porcine samples.
PA1-21146 has been successfully used in immunohistochemistry (paraffin) procedures.
The PA1-21146 immunogen is a synthetic peptidecorresponding to the C-terminal portion of human TIMP-3.
靶标信息
Tissue inhibitor of metalloproteinase 3 (TIMP3) is a member of the tissue inhibitor of metalloproteinases gene family. It functions to inhibit the activity of matrix metalloproteinases (MMP) which degrade components of the extracellular matrix. TIMP3 is expressed upon mitogenic stimulation. It binds irreversibly to zinc-dependent MMPs and inactivates them by binding to their catalytic zinc cofactor. Other functions of TIMP3 include nervous system development, tissue regeneration, and visual perception. In humans, the gene encoding TIMP3 is located on chromosome 22.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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