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FIGURE: 1 / 1
TIP30 Antibody (PA5-96436) in WB
Western blot analysis of TIP30 in extracts of LO2 cells. Samples were incubated with TIP30 Polyclonal antibody (Product # PA5-96436) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-96436
产品规格
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human HTATIP2.
Conjugate
Unconjugated
形式
Liquid
浓度
1.02 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2808238
Product Specific Information
Immunogen sequence: GAEGFVRVDR DYVLKSAELA KAGGCKHFNL LSSKGADKSS NFLYLQVKGE VEAKVEELKF DRYSVFRPGV LLCDRQESRP GEWLVRKFFG SLPDSWASGH SVPVVTVVRA MLNNVVRPRD KQMELLENKA IHDLGKAHGS LKP; Positive Samples: LO2; Cellular Location: Cytoplasm, Nucleus envelope
Target Information
CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: 30 kDa HIV-1 TAT-interacting protein; FLJ26963; HIV-1 Tat interactive protein 2, 30kDa; HIV-1 TAT-interactive protein 2; HTATIP2; Oxidoreductase HTATIP2; short chain dehydrogenase/reductase family 44U, member 1; Tat-interacting protein (30kD)
Gene Aliases: CC3; HTATIP2; SDR44U1; TIP30
UniProt ID: (Human) Q9BUP3
Entrez Gene ID: (Human) 10553
Molecular Function:
oxidoreductase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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