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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human HTATIP2. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.28 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808238 |
Immunogen sequence: GAEGFVRVDR DYVLKSAELA KAGGCKHFNL LSSKGADKSS NFLYLQVKGE VEAKVEELKF DRYSVFRPGV LLCDRQESRP GEWLVRKFFG SLPDSWASGH SVPVVTVVRA MLNNVVRPRD KQMELLENKA IHDLGKAHGS LKP; Positive Samples: LO2; Cellular Location: Cytoplasm, Nucleus envelope
CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 30 kDa HIV-1 TAT-interacting protein; FLJ26963; HIV-1 Tat interactive protein 2, 30kDa; HIV-1 TAT-interactive protein 2; HTATIP2; Oxidoreductase HTATIP2; short chain dehydrogenase/reductase family 44U, member 1; Tat-interacting protein (30kD)
基因别名: CC3; HTATIP2; SDR44U1; TIP30
UniProt ID: (Human) Q9BUP3
Entrez Gene ID: (Human) 10553
分子生物学功能:
oxidoreductase
