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Proteintech
TK1 Polyclonal Antibody
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产品信息
15691-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TK1 Fusion Protein Ag8249 (1-234 aa encoded by BC007986)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSCINLPTV LPGSPSKTRG QIQVILGPMF SGKSTELMRR VRRFQIAQYK CLVIKYAKDT RYSSSFCTHD RNTMEALPAC LLRDVAQEAL GVAVIGIDEG QFFPDIVEFC EAMANAGKTV IVAALDGTFQ RKPFGAILNL VPLAESVVKL TAVCMECFRE AAYTKRLGTE KEVEVIGGAD KYHSVCRLCY FKKASGQPAG PDNKENCPVP GKPGEAVAAR KLFAPQQILQ CSPAN (1-234 aa encoded by BC007986)
靶标信息
Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: EC 2.7.1.21; KITH; thymidine kinase 1 soluble isoform; thymidine kinase 1, soluble; Thymidine kinase, cytosolic; thymidine kinase-1
基因别名: D530002A18Rik; Tk; Tk-1; TK1; Tk1a; Tk1b; TK2
UniProt ID: (Human) P04183, (Rat) P27158, (Mouse) P04184
Entrez Gene ID: (Human) 7083, (Rat) 24834, (Mouse) 21877
liver development
nucleobase-containing compound metabolic process
DNA metabolic process
deoxyribonucleoside monophosphate biosynthetic process
nucleotide biosynthetic process
response to toxic substance
skeletal muscle cell proliferation
phosphorylation
response to nutrient levels
pyrimidine nucleoside salvage
thymidine metabolic process
response to copper ion
digestive tract development
protein homotetramerization
response to cortisol
fetal process involved in parturition
DNA biosynthetic process
