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Invitrogen
TLE4 Polyclonal Antibody
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TLE4 Antibody (PA5-110491) in WB
Western blot analysis of TLE4 in extracts of Rat lung. Samples were incubated with TLE4 Polyclonal antibody (Product # PA5-110491) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
PA5-110491
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 173-243 of human TLE4 (NP_001269677)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SSALGGQSHL PIKDEKKHHD NDHQRDRDSI KSSSVSPSAS FRGAEKHRNS ADYSSESKKQ KTEEKEIAAR Y
靶标信息
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Grg-4; Groucho-related protein 4; Protein ESP2; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4, E(spl) homolog; transducin-like enhancer of split 4, homolog of Drosophila E(spl); Transducin-like enhancer protein 4
基因别名: Esp2; Grg-4; Grg4; Tle4
UniProt ID: (Rat) Q07141
Entrez Gene ID: (Rat) 25565
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
Wnt signaling pathway
negative regulation of transcription, DNA-templated
negative regulation of nucleic acid-templated transcription
