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Invitrogen
TLE4 Recombinant Rabbit Monoclonal Antibody (1D3V4)
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TLE4 Antibody (MA5-55373) in WB
Western Blot analysis of various lysates using TLE4 Recombinant Monoclonal Antibody (Product # MA5-55373) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
MA5-55373
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1D3V4
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human TLE4.
偶联物
形式
Liquid
浓度
1.26 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
RRID
产品详细信息
Immunogen Sequence: MIRDLSKMYP QTRHPAPHQP AQPFKFTISE SCDRIKEEFQ FLQAQYHSLK LECEKLASEK TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP FLSQEHQQQV VQAVERAKQV TMAELNAIIG QQLQAQHL
靶标信息
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B lymphocyte gene 1; enhancer of split groucho 4; Grg-4; Groucho-related protein 4; Protein ESP2; transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4, E(spl) homolog; transducin-like enhancer of split 4, homolog of Drosophila E(sp1); transducin-like enhancer of split 4, homolog of Drosophila E(spl); Transducin-like enhancer protein 4
基因别名: 5730411M05Rik; AA792082; BCE-1; BCE1; E(spI); ESG; ESG4; Esp2; ESTM13; ESTM14; Grg-4; GRG4; KIAA1261; TLE4; X83332; X83333
UniProt ID: (Human) Q04727, (Mouse) Q62441, (Rat) Q07141
Entrez Gene ID: (Human) 7091, (Mouse) 21888, (Rat) 25565
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
biological_process
Wnt signaling pathway
beta-catenin-TCF complex assembly
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
negative regulation of transcription, DNA-templated
negative regulation of nucleic acid-templated transcription
