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Invitrogen
TM7SF3 Polyclonal Antibody
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TM7SF3 Antibody (PA5-144053) in WB
Western blot analysis of TM7SF3 using TM7SF3 antibody (Product # PA5-144053). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human RT4 whole cell lysates; Lane 2: human Jurkat whole cell lysates; Lane 3: human MOLT-4 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat mi... View More
产品信息
PA5-144053
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human TM7SF3 recombinant protein (Position: R102-R544).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human RT4 whole cell, human Jurkat whole cell, human MOLT-4 whole cell. Flow: SiHa cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
The TM7SF3 gene encodes transmembrane 7 superfamily member 3, a protein that is involved in cellular homeostasis and stress responses. TM7SF3 is characterized by its seven transmembrane domains, which contribute to its role in signal transduction across the cell membrane. This gene is expressed in various tissues and has been implicated in regulating cellular growth and survival pathways, proving critical in the context of cellular response to endoplasmic reticulum (ER) stress and maintaining cellular integrity. TM7SF3 modulates processes such as apoptosis and autophagy, particularly under stress conditions, thus influencing both normal physiological processes and pathological states like cancer. Research has shown that TM7SF3 expression can be altered in certain diseases, affecting pathways that govern cell cycle progression and stress adaptation. Understanding the role of TM7SF3 in cellular signaling and stress management can aid in identifying therapeutic targets for conditions characterized by dysfunctional cellular responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Seven span transmembrane protein; seven transmembrane protein TM7SF3; Transmembrane 7 superfamily member 3
基因别名: TM7SF3
UniProt ID: (Human) Q9NS93
Entrez Gene ID: (Human) 51768
