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Invitrogen
TMEM184A Polyclonal Antibody
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TMEM184A Antibody (PA5-96834) in WB
Western blot analysis of TMEM184A in extracts of various cell lines. Samples were incubated with TMEM184A Polyclonal antibody (Product # PA5-96834) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-96834
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 324-413 of human TMEM184A (NP_0010910891)
偶联物
形式
Liquid
浓度
0.49 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FPCQVYAEKK ENSPAPPAPM QSISSGIRET VSPQDIVQDA IHNFSPAYQH YTQQATHEAP RPGTHPSGGS GGSRKSRSLE KRMLIPSEDL; Positive Samples: Mouse lung, Mouse liver, Mouse kidney, Rat lung; Cellular Location: Membrane, Multi-pass membrane protein
靶标信息
TMEM184A, a multi-pass transmembrane protein, belongs to the UPF0206 family. While the exact function of TMEM184A remains unclear, it is known to be expressed at high levels in the developing testis. TMEM184A may mediate sex-specific signaling events during Sertoli cell differentiation. The restricted expression of this gene in Sertoli cells suggests a role for the encoded protein in the development and/or continued function of that cell type. Ectopic expression of TMEM184A in female genital ridges resulted in failure of gonocytes to enter meiosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Sexually dimorphic expressed in male gonads 1; tcag7.540; Transmembrane protein 184A
基因别名: RGD1306702; Sdmg1; Tmem184a
UniProt ID: (Mouse) Q3UFJ6, (Rat) Q4QQS1
Entrez Gene ID: (Mouse) 231832, (Rat) 304325
