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产品信息
PA5-42844
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human TMEM48
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2605724
产品详细信息
Peptide sequence: SFTEDRFGVV QTTLPAILNT LLTLQEAVDK YFKLPHASSK PPRISGSLVD
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
靶标信息
TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
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生物信息学
蛋白别名: FLJ10407; FLJ12556; FLJ34120; hNDC1; nuclear division cycle 1 homolog; Nucleoporin NDC1; RP4-654H19.1; Transmembrane protein 48
基因别名: NDC1; NET3; TMEM48
UniProt ID: (Human) Q9BTX1
Entrez Gene ID: (Human) 55706
mRNA export from nucleus
tRNA export from nucleus
mitotic nuclear envelope disassembly
synapsis
spermatogenesis
regulation of glucose transport
protein transport
viral process
protein sumoylation
viral transcription
spindle pole body duplication
gene silencing by RNA
nuclear pore distribution
nuclear pore complex assembly
establishment of spindle pole body localization to nuclear envelope
intracellular transport of virus
regulation of cellular response to heat
