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Invitrogen
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Immunogen sequence: KLSTPDVVSPF GTPFGSSVMN RMAGIFDVNT CYGSPQSPQL IRRGPRLWTS ASDQQMTEFS NPSPSTSISA E
Highest antigen sequence identity to the following orthologs - mouse 76%, rat 79%.
TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。