Invitrogen

TMPRSS11F Polyclonal Antibody

产品信息

PA5-55461

应用

建议稀释比

已发表文章

免疫组化 (IHC)

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human TMPRSS11F. Recombinant protein control fragment (Product #RP-90611).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2648761

产品详细信息

Immunogen sequence: NKDPTQWIAT FGATITPPAV KRNVRKIILH ENYHRETNEN DIALVQLSTG VEFSNIVQRV CLPDSSIKLP PKTSVFVTGF GSIVDDGPIQ NTLRQARVET ISTDVCNRKD VYDG

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.

靶标信息

TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.

仅用于科研。不用于诊断过程。未经明确授权不得转售。