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Invitrogen
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This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: thioredoxin domain containing 14; Thioredoxin domain-containing protein 14; Thioredoxin-related transmembrane protein 2
基因别名: 2310042M24Rik; AA589631; Tmx2; Txndc14
UniProt ID: (Mouse) Q9D710
Entrez Gene ID: (Mouse) 66958