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Abnova
TNFRSF11A Monoclonal Antibody (2G2)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00008792-M39
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2G2
抗原
TNFRSF11A (NP_003830.1, 31 a.a. approximately 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: APPCTSEKHY EHLGRCCNKC EPGKYMSSKC TTTSDSVCLP CGPDEYLDSW NEEDKCLLHK VCDTGKALVA VVAGNSTTPR RCACTAGYHW SQDCECCRRN
靶标信息
RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD265; ODFR; Osteoclast differentiation factor receptor; receptor activator of NF-kappaB; Receptor activator of NF-KB; Tumor necrosis factor receptor superfamily member 11A
基因别名: Ly109; mRANK; ODFR; OFE; RANK; RGD1563614; TNFRSF11A; TRANCE-R
UniProt ID: (Mouse) O35305
Entrez Gene ID: (Mouse) 21934, (Rat) 498206
ossification
adaptive immune response
multicellular organism development
programmed cell death
osteoclast differentiation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to cytokine
response to tumor necrosis factor
positive regulation of JUN kinase activity
lymph node development
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
circadian temperature homeostasis
mammary gland alveolus development
response to interleukin-1
positive regulation of fever generation by positive regulation of prostaglandin secretion
TNFSF11-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
response to radiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
