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Invitrogen
TNK1 Polyclonal Antibody
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产品信息
PA1-4332
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic Peptide: Q(421) N Q V Q S L P A G S A E P(434)
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-4332 detects Kos1 (a.k.a. TNK1) from mouse samples.
PA1-4332 has been successfully used in Western blot procedures.
PA1-4332 immunizing peptide corresponds to amino acid residues 421-434 from mouse Kos1 Protein.
靶标信息
TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family and as such is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. TNK1 may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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