Invitrogen

TNN Polyclonal Antibody

产品信息

PA5-50579

应用	建议稀释比	已发表文章
免疫组化（石蜡） (IHC (P))	1:50-1:200	-

产品规格
种属反应	Human, Mouse
宿主/亚型	Rabbit / IgG
分类	Polyclonal
类型	Antibody
抗原	Synthetic peptide corresponding to a region derived from internal residues of human tenascin N
偶联物	Unconjugated
形式	Liquid
浓度	1.3 mg/mL
纯化类型	Antigen affinity chromatography
保存液	PBS, pH 7.4, with 40% glycerol
内含物	0.05% sodium azide
保存条件	-20°C
RRID	AB_2636032

产品详细信息

The antibody detects endogenous levels of total TNN protein.

靶标信息

Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (PubMed:17909022). Involved in neurite outgrowth and cell migration in hippocampal explants. During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (PubMed:19884327). Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells (PubMed:17909022). [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。