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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
0.5-1 µg/mL | - |
免疫细胞化学 (ICC/IF) |
Assay-dependent | 查看1篇已发表文章 1篇已发表文章 |
免疫电镜技术 (IM) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Non-human primate |
已发表种属 |
Human |
宿主/亚型 |
Mouse / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
1C9-2 |
抗原 |
Membrane fraction from Vero (monkey kidney-derived) cells. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.2 mg/mL |
纯化类型 |
purified |
保存液 |
0.01M PBS, pH 7.4, with 1% BSA |
内含物 |
15mM sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2303718 |
Recommended positive controls: Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Tom22 has a negatively charged N-terminal region exposed to the cytosol, a putative transmembrane region, and a C-terminal intermembrane space region with little negative charge. The following functions can be assigned to the three domains of Tom22: the cytosolic N-terminal domain plays a dual role, specifically important for presequence binding; the intermembrane space domain provides a trans binding site for presequences, and the single membrane anchor of Tom22 is crucial for the integrity of the GIP (general import gene) complex. The TOM complex of mammalian mitochondria resembles the fungal Tom complex, but is distinct from the plant TOM system. Thus, while unique components of the mammalian mitochondrial import system have been identified (e. g. TOM34 and metaxin), Tom22, and Tom37 have not been identified in plant mitochondria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 1C9-2; hTom22; Mitochondrial import receptor subunit TOM22 homolog; mitochondrial import receptor Tom22; Translocase of outer membrane 22 kDa subunit homolog; translocase of outer mitochondrial membrane 22 homolog
基因别名: 1C9-2; MST065; MSTP065; TOM22; TOMM22
UniProt ID: (Human) Q9NS69
Entrez Gene ID: (Human) 56993
分子生物学功能:
primary active transporter
