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Proteintech
TOP1MT Polyclonal Antibody
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产品信息
16540-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TOP1MT Fusion Protein Ag9857 (253-601 aa encoded by BC052285)
偶联物
形式
Liquid
浓度
0.44 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TESIQNSIK YIMLNPCSKL KGETAWQKFE TARRLRGFVD EIRSQYRADW KSREMKTRQR AVALYFIDKL ALRAGNEKED GEAADTVGCC SLRVEHVQLH PEADGCQHVV EFDFLGKDCI RYYNRVPVEK PVYKNLQLFM ENKDPRDDLF DRLTTTSLNK HLQELMDGLT AKVFRTYNAS ITLQEQLRAL TRAEDSIAAK ILSYNRANRV VAILCNHQRA TPSTFEKSMQ NLQTKIQAKK EQVAEARAEL RRARAEHKAQ GDGKSRSVLE KKRRLLEKLQ EQLAQLSVQA TDKEENKQVA LGTSKLNYLD PRISIAWCKR FRVPVEKIYS KTQRERFAWA LAMAGEDFEF (253-601 aa encoded by BC052285)
靶标信息
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DNA topoisomerase I; DNA topoisomerase I, mitochondrial; mitochondrial topoisomerase IB; TOP1M; TOP1mt; Topoisomerase I mitochondrial; Type IB Topoisomerase
基因别名: TOP1MT
UniProt ID: (Human) Q969P6
Entrez Gene ID: (Human) 116447
