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Invitrogen
TPCN1 Polyclonal Antibody
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TPCN1 Antibody (PA5-90758) in WB
Western blot analysis of TPCN1 in extracts of Rat lung. Samples were incubated with TPCN1 Polyclonal antibody (Product # PA5-90758) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-90758
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 692-816 of human TPCN1 (NP_0603712)
偶联物
形式
Liquid
浓度
2.37 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FRMNYSRKNQ DSEVDGGITL EKEISKEELV AVLELYREAR GASSDVTRLL ETLSQMERYQ QHSMVFLGRR SRTKSDLSLK MYQEEIQEWY EEHAREQEQQ RQLSSSAAPA AQQPPGSRQR SQTVT; Positive Samples: Rat lung; Cellular Location: Endosome membrane, Lysosome membrane, Multi-pass membrane protein
靶标信息
TPCN1 may function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane. Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ20612; Two pore calcium channel protein 1; two pore channel 1; Voltage-dependent calcium channel protein TPC1; voltage-gated Ca channel
基因别名: 5730403B01Rik; Kiaa1169; mKIAA1169; Tpc1; Tpcn1
UniProt ID: (Mouse) Q9EQJ0, (Rat) Q9WTN5
Entrez Gene ID: (Mouse) 252972, (Rat) 246215
