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Proteintech
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Immunogen sequence: MDSAGQDIN LNSPNKGLLS DSMTDVPVDT GVAARTPAVE GLTEAEEEEL RAELTKVEEE IVTLRQVLAA KERHCGELKR RLGLSTLGEL KQNLSRSWHD VQVSSAYVKT SEKLGEWNEK VTQSDLYKKT QETLSQAGQK TSAALSTVGS AISRKLGDMR NSATFKSFED RVGTIKSKVV GDRENGSDNL PSSAGSGDKP LS (1-201 aa encoded by BC006804)
EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686A1765; HCCR-binding protein 2; hD54; Tumor protein D52-like 2; Tumor protein D54
基因别名: 2810411G23Rik; AU016537; C86069; D54; TPD52L2; TPD54
UniProt ID: (Human) O43399, (Rat) Q6PCT3, (Mouse) Q9CYZ2
Entrez Gene ID: (Human) 7165, (Rat) 296480, (Mouse) 66314