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Proteintech
TPRKB Polyclonal Antibody
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产品信息
12800-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TPRKB Fusion Protein Ag3551 (1-175 aa encoded by BC029492)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is a rabbit polyclonal antibody raised against full length TPRKB of human origin.
Immunogen sequence: MQLTHQLDL FPECRVTLLL FKDVKNAGDL RRKAMEGTID GSLINPTVIV DPFQILVAAN KAVHLYKLGK MKTRTLSTEI IFNLSPNNNI SEALKKFGIS ANDTSILIVY IEEGEKQINQ EYLISQVEGH QVSLKNLPEI MNITEVKKIY KLSSQEESIG TLLDAIICRM STKDVL (1-175 aa encoded by B C029492)
靶标信息
TPRKB is a component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EKC/KEOPS complex subunit TPRKB; PRPK (p53-related protein kinase)-binding protein; PRPK-binding protein; TP53RK-binding protein; WBSCR18
基因别名: 0610033G21Rik; 1810034M08Rik; CGI-121; CGI121; DRWMS1; mDRWMS1; My019; RGD1309786; TPRKB
UniProt ID: (Human) Q9Y3C4, (Mouse) Q8QZZ7
Entrez Gene ID: (Human) 51002, (Mouse) 69786, (Rat) 297411
