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产品信息
PA5-64938
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human TRAK1 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.2 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2665179 |
产品详细信息
Immunogen sequence: CTPRRLSLAES FTNTRESTTT MSTSLGLVWL LKERGISAAV YDPQSWDRAG RGSLLHSYTP KMAVIPSTPP NSPMQTPTSS PPSFEFKCTS PPYDNFLASK PASSILREVR EKNVRSSESQ TDVSVSNLNL VD
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
靶标信息
Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes. TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 106 kDa O-GlcNAc transferase-interacting protein; milton homolog 1; O-linked N-acetylglucosamine transferase interacting protein 106; OGT(O-Glc-NAc transferase)-interacting protein 106 KDa; Protein Milton; Trafficking kinesin-binding protein 1; trafficking protein, kinesin binding 1
基因别名: KIAA1042; MILT1; OIP106; TRAK1
UniProt ID: (Human) Q9UPV9
Entrez Gene ID: (Human) 22906
分子生物学功能:
membrane traffic protein
