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Product Details
PA5-42774
产品规格
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human TRAPPC10
Conjugate
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2608689
Product Specific Information
Peptide sequence: IVDKIRNDFC NKQSDRCVVL SDPLKDSSRT QESWNAFLTK LRTLLLMSFT
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%
Target Information
TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein) or GT334, is a widely expressed 1,259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein and its structure and function appears to be conserved. Localizing to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Mutations in the gene encoding TRAPPC10 may be involved in autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive type of progressive myoclonic epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: EHOC-1; Epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; Protein GT334; Trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 130; Trafficking protein particle complex subunit TMEM1; transmembrane protein 1; Transport protein particle subunit TMEM1; TRAPP 130 kDa subunit; TRAPP subunit TMEM1
Gene Aliases: EHOC-1; EHOC1; GT334; TMEM1; TRAPPC10; TRS130; TRS30
UniProt ID: (Human) P48553
Entrez Gene ID: (Human) 7109
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