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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1 µg/mL | - |
流式细胞分析 (Flow) |
2.5 µg/1x10^6 cells | - |
酶联免疫吸附实验 (ELISA) |
0.1-0.4 µg/mL (Detection), 0.2-0.8 µg/mL (Capture) | - |
功能检测 (FN) |
Assay-Dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Goat / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Sf 21-derived recombinant human TREM-1 Met1-Arg200 |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
0.2 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS with 5% trehalose |
内含物 |
No Preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2577120 |
In ELISAs, less than 0.2% cross-reactivity with recombinant mouse (rm) TREM-1 and rmTREM-2b is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CD354; sCD354; soluble CD354; soluble TREM 1; soluble TREM1; sTREM 1; sTREM1; TREM; TREM-1; Triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells; Triggering receptor expressed on myeloid cells 1
基因别名: CD354; TREM-1; TREM1
UniProt ID: (Human) Q9NP99
Entrez Gene ID: (Human) 54210
