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Invitrogen
TRH Polyclonal Antibody
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产品信息
PA5-89851
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 143-242 of human TRH (NP_0090481)
偶联物
形式
Liquid
浓度
0.58 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: U-87MG, BXPC-3, A-549, DU145, Mouse brain, Rat testis
Immunogen sequence: WLAYAVPKRQ HPGRRLADPK AQRSWEEEEE EEEREEDLMP EKRQHPGKRA LGGPCGPQGA YGQAGLLLGL LDDLSRSQGA EEKRQHPGRR AAWVREPLEE
靶标信息
This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin; protirelin; thyrotropin releasing hormone; thyrotropin-releasing factor; thyrotropin-releasing hormone; TSH-releasing factor
基因别名: Pro-TRH; THR; TRF; TRH; TRH01
UniProt ID: (Human) P20396, (Rat) P01150, (Mouse) Q62361
Entrez Gene ID: (Human) 7200, (Rat) 25569, (Mouse) 22044
response to hypoxia
histamine metabolic process
signal transduction
cell-cell signaling
adult walking behavior
response to cold
response to glucose
hormone-mediated signaling pathway
negative regulation of glutamate secretion
positive regulation of gamma-aminobutyric acid secretion
positive regulation of insulin secretion
eating behavior
response to ethanol
response to corticosterone
negative regulation of feeding behavior
response to organic cyclic compound
