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Proteintech
TRIM22 Polyclonal Antibody
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产品信息
13744-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TRIM22 Fusion Protein Ag4683 (1-350 aa encoded by BC035582)
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDFSVKVDI EKEVTCPICL ELLTEPLSLD CGHSFCQACI TAKIKESVII SRGESSCPVC QTRFQPGNLR PNRHLANIVE RVKEVKMSPQ EGQKRDVCEH HGKKLQIFCK EDGKVICWVC ELSQEHQGHQ TFRINEVVKE CQEKLQVALQ RLIKEDQEAE KLEDDIRQER TAWKNYIQIE RQKILKGFNE MRVILDNEEQ RELQKLEEGE VNVLDNLAAA TDQLVQQRQD ASTLISDLQR RLRGSSVEML QDVIDVMKRS ESWTLKKPKS VSKKLKSVFR VPDLSGMLQV LKELTDVQYY WVDVMLNPGS ATSNVAISVD QRQVKTVRTC TFKNSNPCDF SAFGVFGCQY F (1-350 aa encoded by BC035582)
靶标信息
TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 50 kDa-stimulated trans-acting factor; E3 ubiquitin-protein ligase TRIM22; RING finger protein 94; RING-type E3 ubiquitin transferase TRIM22; Staf-50; stimulated trans-acting factor (50 kDa); tripartite binding motif 22; tripartite motif protein TRIM22; tripartite motif-containing 22; Tripartite motif-containing protein 22
基因别名: GPSTAF50; RNF94; STAF50; TRIM22
UniProt ID: (Human) Q8IYM9
Entrez Gene ID: (Human) 10346
transcription, DNA-templated
regulation of transcription, DNA-templated
immune response
response to virus
positive regulation of autophagy
protein ubiquitination
regulation of protein localization
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
defense response to virus
interferon-gamma-mediated signaling pathway
protein trimerization
negative regulation of nucleic acid-templated transcription
