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Sequence homology: Cow: 79%; Horse: 83%; Human: 100%; Mouse: 79%; Pig: 79%; Rabbit: 79%; Rat: 79%
TRIM6 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A read-through transcript transcribed from this gene and TRIM34 has been observed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RING finger protein 89; RING-type E3 ubiquitin transferase TRIM6; tripartite motif-containing 6; Tripartite motif-containing protein 6
基因别名: RNF89; TRIM6
UniProt ID: (Human) Q9C030
Entrez Gene ID: (Human) 117854
分子生物学功能: ubiquitin-protein ligase