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Invitrogen
TRIM62 Polyclonal Antibody
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TRIM62 Antibody (PA5-116643) in IHC (P)
Immunohistochemistry analysis of TRIM62 in paraffin-embedded human colon. Samples were incubated with TRIM62 Polyclonal antibody (Product # PA5-116643) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-116643
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human TRIM62 (NP_0606772)
偶联物
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: A-431, Mouse brain
Immunogen sequence: HEQHQVTGID DAFDELQREL KDQLQALQDS EREHTEALQL LKRQLAETKS STKSLRTTIG EAFERLHRLL RERQKAMLEE LEADTARTLT DIEQKVQRYS QQLRKVQEGA QILQERLAET DRHTFLAGVA SLSERLKGKI HETNLTYEDF PTSKYTGPLQ Y
靶标信息
E3 ubiquitin ligase whose activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ductal epithelium-associated RING Chromosome 1; E3 ubiquitin-protein ligase TRIM62; tripartite motif-containing 62; Tripartite motif-containing protein 62
基因别名: 6330414G21Rik; AI450348; DEAR1; TRIM62
UniProt ID: (Human) Q9BVG3, (Mouse) Q80V85
Entrez Gene ID: (Human) 55223, (Rat) 313045, (Mouse) 67525
ubiquitin-protein transferase activity
zinc ion binding
ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
negative regulation of epithelial to mesenchymal transition
protein ubiquitination
negative regulation of viral transcription
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
regulation of viral entry into host cell
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
interferon-gamma-mediated signaling pathway
regulation of viral release from host cell
