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Invitrogen
TROY (extracellular) Polyclonal Antibody
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TROY (extracellular) Antibody (PA5-111871) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of TROY in live intact human U-87 MG cells. A) Extracellular staining of cells using TROY (extracellular) Antibody (Product # PA5-111871) (1:25), followed by goat anti-rabbit-AlexaFluor-488 secondary antibody (green). B) Live view of the cells. C) Merge of A and B.
产品信息
PA5-111871
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to amino acid residues 75-88 of mouse TROY (Extracellular, N-terminus)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: CRPHRFKEDW GFQK
Homology: Rat, human - 13/14 amino acid residues identical.
靶标信息
Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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