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Immunogen sequence: LLNLYSLVYN EDKKNTMGPA LERIDYLLIL WIIGMIWSDI KRLWYEGLED FLEESRNQLS FVMNSLYLAT FALKVVAHNK FHDFADRKDW DAFHPTLVAE G
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 3010009O07Rik; AI115608; capacitative calcium channel protein Trp1; membe; mTrp2; Short transient receptor potential channel 1; smTRPC2; transient receptor potential canonical 1; transient receptor potential cation channel, subfamily C, member 1; Transient receptor protein 1; TRP-1; TRP-1 protein; Trp-related protein 1; trp2; TrpC1; TRPC2a; TRPC2b; Trrp2
基因别名: HTRP-1; Mtrp1; TRP1; TRPC1; Trrp1
UniProt ID: (Human) P48995, (Mouse) Q61056
Entrez Gene ID: (Human) 7220, (Mouse) 22063
分子生物学功能: ion channel transporter