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Alomone Labs, LTD
TRPC3 Polyclonal Antibody
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TRPC3 Antibody (ACC-016-GP200UL) in IHC (F)
Expression of TRPC3 in mouse cerebellum. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Guinea pig Anti-TRPC3 Antibody &(8)239; (#ACC-016-GP), (1:200), followed by goat Anti-guinea pig-AlexaFluor-594. A. TRPC3 immunoreactivity (red) appears in purkinje cells (arrows). B. Pre-incubation of the Antibody with TRPC3 Blocking Peptide (#BLP-CC016), suppressed staining. Cell nucle... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
ACC-016-GP200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Guinea pig
/ IgG
分类
Polyclonal
类型
Antibody
抗原
HKLSEKLNPSVLRC, corresponding to amino acid residues 822-835 of mouse TRPC3, Intracellular, C-terminus
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.85 mg/mL
规格
170 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hTrp3; ion channel protein; mTrp3; receptor-activated cation channel TRP3; splice variant c of Trpc3 ion channel subunit; transient receptor protein 3; TRP-3; trp-related protein 3; TRPC3; TRPC3c; unnamed protein product
基因别名: Mwk; Trcp3; Trp3; TrpC3c; Trrp3
UniProt ID: (Rat) Q9JMI9, (Mouse) Q9QZC1
Entrez Gene ID: (Rat) 60395, (Mouse) 22065
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