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Invitrogen
TRPM2 Polyclonal Antibody
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产品信息
OSR00131W
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from the 4th cytoplasmic domain of human TRPM2
偶联物
形式
Lyophilized
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Reconstitute with 100 µL of distilled water.
Centrifuge to remove any insoluble material.
靶标信息
TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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