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Invitrogen
TRPM2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-111058
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.50 mg/mL
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RTRLEKFISE QTKERGGVAI KIPIVCVVLE GGPGTLHTID NATTNGTPCV VVEGSGRVAD VIAQVANLPV SDITISLIQQ KLSVFFQEMF ETFTESRIVE WTKKIQDIVR RRQLLTVFRE GKDGQQDV
Highest antigen sequence indentity to the following orthologs: Mouse - 91%, Rat - 94%.
靶标信息
TRPM2 belongs to the ion transport protein family which includes Sodium, Potassium, Calcium ion channels. This family is characterized by proteins possessing 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death. Further, TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. Several alternatively spliced transcript variants of the TRPM2 gene have been described, but their full-length nature is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 3.6.1.13; EREG 1; Estrogen-responsive element-associated gene 1 protein; KNP 3; Long transient receptor potential channel 2; LTRPC 2; LTrpC-2; MGC133383; Transient receptor potential cation channel subfamily M member 2; Transient receptor potential channel 7; Transient receptor potential melastatin 2; TRPC 7; TrpC7; TRPM 2
基因别名: EREG1; KNP3; LTRPC2; TRPC7; TRPM2
Entrez Gene ID: (Human) 7226
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