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Alomone Labs, LTD
TRPM7 Polyclonal Antibody
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TRPM7 Antibody (ACC-047-200UL) in ICC/IF
Expression of TRPM7 in GH3 cell lines - Immunocytochemical staining of GH3 cells with Anti-TRPM7 Antibody (#ACC-047), (1:100), followed by goat Anti-rabbit-AlexaFluor-550 secondary Antibody (A). B. Nuclear staining of GH3 cells with the cell-permeable dye Hoechst 33342. C. Live intact GH3 cells.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
ACC-047-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CKRRKKDKTSDGPKLFLTEE, corresponding to amino acid residues 1146-1165 of human TRPM7, Intracellular, C-terminus
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.8 mg/mL
规格
160 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ChaK1; melanoma alpha-kinase; Channel kinase 1; channel-kinase 1; FLJ20117; ion channel; protein kinase; TRP-PLIK; long transient receptor potential channel 7; LTRPC ion channel family member 7; member of LTRPC ion channel family; tr; transient receptor potential M7; transient receptor potential-phospholipase C-interacting kinase; transient receptor potential-related protein, ChaK; TRMP7; TRP PLIK; trp-related; unnamed protein product
基因别名: 2310022G15Rik; 4833414K03Rik; 5033407O22Rik; ALSPDC; CHAK; CHAK1; Ltpr7; LTrpC-7; LTRPC7; TRP-PLIK; TRPPLIK
UniProt ID: (Human) Q96QT4, (Mouse) Q923J1, (Rat) Q925B3
Entrez Gene ID: (Human) 54822, (Mouse) 58800, (Rat) 679906
actin binding
protein kinase activity
protein serine/threonine kinase activity
calcium channel activity
zinc ion transmembrane transporter activity
protein binding
ATP binding
calcium ion transmembrane transporter activity
magnesium ion transmembrane transporter activity
kinase activity
myosin binding
protein serine kinase activity
cation channel activity
cation transmembrane transporter activity
protein phosphorylation
calcium ion transport
zinc II ion transport
memory
magnesium ion homeostasis
cellular magnesium ion homeostasis
magnesium ion transport
calcium-dependent cell-matrix adhesion
metal ion transport
actomyosin structure organization
positive regulation of apoptotic process
protein autophosphorylation
protein tetramerization
protein homotetramerization
necroptotic process
calcium ion transmembrane transport
zinc II ion transmembrane transport
cation transmembrane transport
magnesium ion transmembrane transport
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