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Invitrogen
TRPML1 Polyclonal Antibody
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TRPML1 Antibody (OSR00050W) in IHC (P)
Immunohistochemistry (Paraffin) analysis was performed in sections of rat brain using TRPML1 Polyclonal Antibody (Product #OSR00050W). The animal was perfused using Autoperfuser at a pressure of 110 mmHg with 300 ml 4% FA and further post fixed overnight before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. P... View More
产品信息
OSR00050W
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from aa 150-210 of mouse Mucolipin 1 conjugated to blue carrier protein was used as the antigen.
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Glycerol (1:1) may be added for additional stability.
Reconstitute in 100 µL of sterile water.
OSR00050W can be used with blocking peptide GSM00003P.
靶标信息
Defects in Mucolipin-1 are the cause of mucolipidosis type IV (MLIV), also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration and strabismus. Storage bodies of lipids and water-soluble substances are seen by electron microscopy in almost every cell type of the patients. Most patients are unable to speak or walk independently and reach a maximal developmental level of 1-2 years. All patients have constitutive achlorhydia associated with a secondary elevation of serum gastrin levels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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