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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 95%, Rat- 95%.
Sequence of this protein is as follows: VLLGIPYDPK KYDVWSMGVV LYVMVTGCMP FDDSDIAGLP RRQKRGVLYP EGLELSERCK ALIAELLQFS PSARPSAGQV ARNCWLR
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cancer/testis antigen 72; CT72; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase; Testis-specific serine/threonine-protein kinase 6; TSK-6
基因别名: FKSG82; SSTK; TSSK6
Entrez Gene ID: (Human) 83983