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Proteintech
TTRAP Polyclonal Antibody
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产品信息
12203-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TTRAP Fusion Protein Ag2846 (1-362 aa encoded by BC017553)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MELGSCLEG GREAAEEEGE PEVKKRRLLC VEFASVASCD AAVAQCFLAE NDWEMERALN SYFEPPVEES ALERRPETIS EPKTYVDLTN EETTDSTTSK ISPSEDTQQE NGSMFSLITW NIDGLDLNNL SERARGVCSY LALYSPDVIF LQEVIPPYYS YLKKRSSNYE IITGHEEGYF TAIMLKKSRV KLKSQEIIPF PSTKMMRNLL CVHVNVSGNE LCLMTSHLES TRGHAAERMN QLKMVLKKMQ EAPESATVIF AGDTNLRDRE VTRCGGLPNN IVDVWEFLGK PKHCQYTWDT QMNSNLGITA ACKLRFDRIF FRAAAEEGHI IPRSLDLLGL EKLDCGRFPS DHWGLLCNLD IIL (1-362 aa encoded by BC017553)
靶标信息
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5'-Tyr-DNA phosphodiesterase; 5'-tyrosyl-DNA phosphodiesterase; EAPII; ETS1-associated protein 2; ETS1-associated protein II; MGC111021; MGC9099; RP1-30M3.3; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; Tyr-DNA phosphodiesterase 2; Tyrosyl-DNA phosphodiesterase 2; Tyrosyl-RNA phosphodiesterase; VPg unlinkase
基因别名: AD-022; AD022; D13Ertd656e; dJ30M3.3; EAP2; EAPII; hTDP2; TDP2; TTRAP
UniProt ID: (Human) O95551, (Mouse) Q9JJX7, (Rat) Q3T1H5
Entrez Gene ID: (Human) 51567, (Mouse) 56196, (Rat) 498749
magnesium ion binding
single-stranded DNA binding
transcription corepressor activity
nuclease activity
protein binding
manganese ion binding
tyrosyl-RNA phosphodiesterase activity
5'-tyrosyl-DNA phosphodiesterase activity
cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
photoreceptor cyclic-nucleotide phosphodiesterase activity
endonuclease activity
phosphoric diester hydrolase activity
hydrolase activity
7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity
metal ion binding
inositol phosphosphingolipid phospholipase activity
inositol phosphorylceramide phospholipase activity
mannosyl-inositol phosphorylceramide phospholipase activity
mannosyl-diinositol phosphorylceramide phospholipase activity
