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产品信息
PA5-64973
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫细胞化学 (ICC/IF) |
0.25-2 µg/mL | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human TULP3 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.5 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2662208 |
产品详细信息
Immunogen sequence: QAKLDYQRLLL EKRQRKKRLE PFMVQPNPEA RLRRAKPRAS DEQTPLVNCH TPHSNVILHG IDGPAAVLKP DEVHAPSVSS SVVEEDAENT VDTASKPGLQ ERLQKHDISE SVNFDEETDG ISQSACLERP NSASSQ
Highest antigen sequence identity to the following orthologs - mouse 54%, rat 56%.
靶标信息
This gene encodes a member of the tubby-like protein (TULP) family. Members of this family have been identified in plants, vertebrates, and invertebrates, and they share a conserved C-terminal region of approximately 200 amino acid residues. The human and mouse TULP3 proteins share 69% amino acid sequence identity, with higher identity at the N and C termini than in the central region.
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生物信息学
蛋白别名: Tubby-like protein 3; Tubby-related protein 3
基因别名: TUBL3; TULP3
UniProt ID: (Human) O75386
Entrez Gene ID: (Human) 7289
neural tube closure
regulation of transcription, DNA-templated
G-protein coupled receptor signaling pathway
brain development
regulation of G-protein coupled receptor protein signaling pathway
anterior/posterior pattern specification
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
central nervous system neuron differentiation
embryonic camera-type eye development
embryonic digit morphogenesis
negative regulation of smoothened signaling pathway
embryonic neurocranium morphogenesis
bone development
bronchus morphogenesis
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
ganglion development
receptor localization to nonmotile primary cilium
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
protein localization to photoreceptor outer segment
