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Proteintech
TUSC2 Polyclonal Antibody
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产品信息
11538-1-AP
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TUSC2 Fusion Protein Ag2118 (1-110 aa encoded by BC023976)
偶联物
形式
Liquid
浓度
0.15 mg/mL
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MGASGSKAR GLWPFASAAG GGGSEAAGAE QALVRPRGRA VPPFVFTRRG SMFYDEDGDL AHEFYEETIV TKNGQKRAKL RRVHKNLIPQ GIVKLDHPRI HVDFPVILYE V (1-110 aa encoded by BC023976)
靶标信息
TUSC2 (tumor suppressor candidate 2), also known as FUS1, LGCC or PDAP2, is a 110 amino acid protein that is expressed at high levels in kidney, pancreas, lung, heart and skeletal muscle where it is thought to function as a tumor suppressor. More specifically, TUSC2 inhibits invasive colony formation by inducing G1 cell cycle arrest and ultimately causing apoptosis, thereby preventing tumor growth. The gene encoding TUSC2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
