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Invitrogen
TWF2 Polyclonal Antibody
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TWF2 Antibody (PA5-96451) in WB
Western blot analysis of TWF2 in extracts of various cell lines. Samples were incubated with TWF2 Polyclonal antibody (Product # PA5-96451) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
PA5-96451
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of human TWF2 (NP_009215.1).
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MAHQTGIHAT EELKEFFAKA RAGSVRLIKV VIEDEQLVLG ASQEPVGRWD QDYDRAVLPL LDAQQPCYLL YRLDSQNAQG FEWLFLAWSP DNSPVRLKML YAATRATVKK EFGGGHIKDE LFGTVKDDLS FAGYQKHLSS CAAPAPLTSA ERELQQIRIN EVKTEISVES KHQTLQGLAF PLQPEAQRAL QQLKQKMVNY IQMKLDLERE TIELVHTEPT DVAQLPSRVP RDAARYHFFL YKHTHEGDPL ESVVFIYSMP GYKCSIKERM LYSSCKSRLL DSVEQDFHLE IAKKIEIGDG AELTAEFLYD EVHPKQHAFK QAFAKPKGPG GKRGHKRLIR GPGENGDDS; Positive Samples: Jurkat, 293T, HepG2, A-431, Mouse heart, Mouse thymus, Mouse skeletal muscle; Cellular Location: Cell projection, Cytoplasm, cytoskeleton, perinuclear region, stereocilium
靶标信息
TWF2 encodes a protein that was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin, a conserved actin monomer-binding protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A6 related protein; A6-related protein; hA6RP; mA6RP; protein tyrosine kinase 9 related protein; Protein tyrosine kinase 9-like; protein tyrosine kinase 9-like (A6-related protein); PTK 9L; PTK9 protein typrotein tyrosine kinase 9-like (A6-related protein); PTK9L protein tyrosine kinase 9-like (A6-related protein); TWF 2; Twinfilin 2; twinfilin actin-binding protein 2; twinfilin, actin-binding protein, homolog 2; Twinfilin-1-like protein; Twinfilin-2; Twinfilin2
基因别名: A6-related; A6r; A6RP; AU014993; MSTP011; PTK9L; Ptk9r; TWF2
UniProt ID: (Human) Q6IBS0, (Mouse) Q9Z0P5
Entrez Gene ID: (Human) 11344, (Mouse) 23999
positive regulation of lamellipodium assembly
positive regulation of neuron projection development
cell projection organization
negative regulation of actin filament polymerization
regulation of microvillus length
regulation of actin cytoskeleton organization
sequestering of actin monomers
positive regulation of axon extension
barbed-end actin filament capping
cellular response to retinoic acid
cellular response to growth factor stimulus
cell-cell adhesion
multicellular organism development
intracellular signal transduction
