Proteintech

TWSG1 Polyclonal Antibody

Name: TWSG1 Polyclonal Antibody
Brand: Proteintech
SKU: 12327-1-AP

查看其他7个TSG抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (12)

TWSG1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TWSG1 Antibody (12327-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human kidney tissue slide using 12327-1-AP ( TWSG1 Antibody) at dilution of 1:50 (under 40x lens).

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Immunogen image

Immunogen Image TWSG1 Polyclonal Antibody

产品信息

12327-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200-1:1,000

免疫组化（石蜡） (IHC (P))

1:20-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

TWSG1 Fusion Protein Ag2983 (14-223 aa encoded by BC020490)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.19 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

The MW of this protein is 45 kDa, and this antibody specifically recognizes the 45 kDa protein.

Immunogen sequence: LMFLTWLPE SLSCNKALCA SDVSKCLIQE LCQCRPGEGN CSCCKECMLC LGALWDECCD CVGMCNPRNY SDTPPTSKST VEELHEPIPS LFRALTEGDT QLNWNIVSFP VAEELSHHEN LVSFLETVNQ PHHQNVSVPS NNVHAPYSSD KEHMCTVVYF DDCMSIHQCK ISCESMGASK YRWFHNACCE CIGPECIDYG SKTVKCMNCM F (14-223 aa encoded by BC020490)

靶标信息

TWSG1 may be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.

仅用于科研。不用于诊断过程。未经明确授权不得转售。