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Invitrogen
TYROBP Polyclonal Antibody
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TYROBP Antibody (PA5-28803) in WB
Western Blot was performed using Anti-TYROBP Polyclonal Antibody (Product # PA5-28803) and a 12 and 11 kDa band corresponding to TYRO protein tyrosine kinase-binding protein, along with an uncharacterized band (*), was observed across positive model THP 1 differentiated to macrophage, and not in any other cell line. Membrane enriched extracts (50 µg lysate) of THP-1 (Lane 1), THP-1 differentiated to macrophage (Lane 2), SH-SY5Y (Lane 3), Raji (Lane 4) and HT-29 (Lane 5) were electrophoresed using Novex™ 16% Tricine Protein Gel (Product # E... View More
产品信息
PA5-28803
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 50 and 113 of Human DAP12
偶联物
形式
Liquid
浓度
0.65 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Recommended positive controls: DAP12 tansfected 293T cell.
Predicted reactivity: Dog (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
DAP12 is a transmembrane adaptor protein that is non-covalently associated with several cell surface receptors on natural killer (NK), myeloid, and presumably neuronal cells. DAP12 contains an ITAM domain that preferentially recruits the protein tyrosine kinase Syk to initiate signal transduction. Deficiency of DAP12 results in reduced antigen presentation function by myeloid cells and defects in function of certain NK cell receptors in mice, as well as presenile dementia and bone cysts in humans.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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