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Immunogen sequence: TSFTTGGLRI PFPRDCGEEM QNGAGASRTS TIFLNGNRER PLNVFCDMET DGGGWLVFQR RMDGQTDFWR DWEDYAHGFG NISGEFWLGN EALHSLTQAG DYSMRVDLRA GDEAVFAQYD SFHVDSAAEY YRLHLEGYHG TAGDSMSYHS GSVFSARDRD PNSLLISCAV SYRGAWWYRN CHYANLNGLY GSTVDHQGVS WYHWKGFEFS VPFTEMKLRP RNFRSPAGGG; Positive Samples: Mouse liver, Mouse kidney, Rat liver; Cellular Location: extracellular matrix, extracellular space
Tenascin-X (TNXB) is a extracellular matrix glycoprotein predominantly located in the outer reticular lamina of the basement membrane (BM). It interacts with many other ECM proteins and it accelerates collagen fibrillogenesisin vitro. TNXB plays a role in interactions between cell and ECM, antiadhesive effect, inhibiting cell migration, and in maintaining homeostasis of the extracellular matrix. Deficiency of TNXB has been associated with the connective tissue disorder Ehlers-Danlos syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: tenascin-X; TNXB2tenascin XB1; TNXBSTNXTENX; XB-S; XBTN-X
基因别名: Tn-mhc; Tnx
Entrez Gene ID: (Rat) 415089, (Mouse) 81877